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Science International Vol. 5 (3), 2017
Research Article
Study on Conventional and Molecular Diagnostic Tools for Genital Tuberculosis Associating with Infertility in Indian Women
Gargi Kumari , Divya Goel , Amit Kumar Mani Tiwari and Sanjay Mishra
 
Abstract: Background and Objective: Mycobacterium tuberculosis, the etiological agent for tuberculosis has been comprehensively studied for over a century now. But the disease still remains a major public health concern today in the 21st century. The précised and authenticated diagnosis is mandatorily pre-requisite to proper medication and cure of tuberculosis that specifically interferes and thus complicating physiological and biochemical mechanism of setting pregnancy in Indian women ranging between the ages of 18-40 years. Materials and Methods: Out of 700, 400 females were finally recruited on the basis of inclusion and exclusion criteria. Further, various combinations of conventional and modern diagnostic tools were considered and monitored for the best possible option supported by statistical analyses. Results: It was observed that all the 37 laparoscopy positives were also deoxyribonucleic acid-polymerase chain reaction positive during the present study. Conclusion: Data obtained from the present study provides new insights into polymerase chain reaction with modified and advanced protocol likely to be competent as a novel molecular diagnostic technique for rapid and précised diagnosis of genital tuberculosis causing infertility in developing countries.
 
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