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Science International Vol. 1 (6), 2013
Research Article
Study of Biocompatibility and Survival of WJ-Stem Cells on Corroded Surfaces of Ti6Al4V and AISI 316L Bio-metallic Alloys in DMEM Medium Culture
Abbas Fazel Anvari-Yazdi and Azadeh Zamani
 
Abstract: This study was performed to identify the growth behavior and survival of Wharton’s Jelly Mesenchymal Stem Cells (WJ-MSCs) on corroded surfaces of Bio-metallic alloys of Ti6Al4V and AISI 316L for biomedical applications and bone tissue regeneration. The bioactivity of WJ-MSCs and growth rate was studied in contact with corrosion products on surface of aforementioned alloys by Fluorescent Microscopy which revealed that the cells proliferation is more widespread on Ti6Al4V than AISI 316L. Biocorrosion study of mentioned alloys was carried out in essential medium culture of Dulbecco’s Modified Eagle Medium (DMEM, pH~7.2) at temperature of 37°. Electrochemical corrosion tests on both alloys indicate that the formation of passive layer on Ti6Al4V and as a result its pitting resistivity will be higher in comparison to AISI 316L. Also, polarization analysis, Scanning Electron Microscopy (SEM) and Energy Dispersive Spectroscopy (EDS) results prove that AISI 316L is very sensitive to pitting corrosion in DMEM medium culture.
 
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